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Geoffrey H Holm Selected Research

Reoviridae Infections

1/201825-Hydroxycholesterol Production by the Cholesterol-25-Hydroxylase Interferon-Stimulated Gene Restricts Mammalian Reovirus Infection.
6/2013Interferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry.
7/2010Bid regulates the pathogenesis of neurotropic reovirus.
7/2007Retinoic acid-inducible gene-I and interferon-beta promoter stimulator-1 augment proapoptotic responses following mammalian reovirus infection via interferon regulatory factor-3.
2/2006Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus.

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Geoffrey H Holm Research Topics

Disease

5Reoviridae Infections
01/2018 - 02/2006
4Virus Diseases (Viral Diseases)
01/2018 - 07/2007
4Infections
01/2018 - 03/2009
1Myocarditis (Carditis)
07/2010
1Acquired Immunodeficiency Syndrome (AIDS)
05/2007
1Heart Diseases (Heart Disease)
02/2006

Drug/Important Bio-Agent (IBA)

3Antiviral Agents (Antivirals)IBA
01/2018 - 07/2007
3InterferonsIBA
01/2018 - 06/2013
2NF-kappa B (NF-kB)IBA
07/2010 - 02/2006
2Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA
07/2010 - 07/2007
1Viral RNAIBA
01/2018
125-hydroxycholesterolIBA
01/2018
1Nucleic AcidsIBA
01/2018
1Proteins (Proteins, Gene)FDA Link
01/2018
1Interferon Type IIBA
06/2013
1Small Interfering RNA (siRNA)IBA
06/2013
1Death Domain ReceptorsIBA
07/2010
1gamma Subunit Interferon-Stimulated Gene Factor 3 (Interferon Stimulated Gene Factor 3, gamma Subunit)IBA
03/2009
1Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2007
1Interferon-betaIBA
07/2007
1CytokinesIBA
07/2007
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
05/2007
1NF-KappaB Inhibitor alphaIBA
02/2006
1Interleukin-6 (Interleukin 6)IBA
02/2006
1Chemokine CCL5IBA
02/2006
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2006